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Cheap Flights from Myrtle Beach to Key West

Find the cheapest flight options from Myrtle Beach to Key West over the next three months. Book one-way tickets from AED 423 and round-trip tickets from AED 982.

      • MYR 16:00
        4h 6m
        1 stop
        EYW 20:06
        Myrtle Beach - Key West | Sat, Dec 13 | Delta Air Lines
        EYW 07:40
        6h 15m
        1 stop
        MYR 13:55
        Key West - Myrtle Beach | Wed, Dec 17 | Delta Air Lines
        AED 982 AED 3,160
        69% OFF
        69% OFF
        AED 3,160 AED 982
      • MYR 14:39
        5h 27m
        1 stop
        EYW 20:06
        Myrtle Beach - Key West | Thu, Dec 18 | Delta Air Lines
        EYW 11:47
        6h 27m
        1 stop
        MYR 18:14
        Key West - Myrtle Beach | Mon, Dec 22 | Delta Air Lines
        AED 1,107 AED 3,160
        65% OFF
        65% OFF
        AED 3,160 AED 1,107
      • MYR 16:20
        4h 38m
        1 stop
        EYW 20:58
        Myrtle Beach - Key West | Sat, Dec 20 | Delta Air Lines
        EYW 07:25
        5h 6m
        1 stop
        MYR 12:31
        Key West - Myrtle Beach | Wed, Dec 24 | Delta Air Lines
        AED 1,116 AED 3,160
        65% OFF
        65% OFF
        AED 3,160 AED 1,116
      • MYR 14:15
        5h 29m
        1 stop
        EYW 19:44
        Myrtle Beach - Key West | Thu, Jan 8 | Delta Air Lines
        EYW 07:00
        6h 29m
        1 stop
        MYR 13:29
        Key West - Myrtle Beach | Sun, Jan 11 | Delta Air Lines
        AED 1,345
        56% OFF
        AED 3,160 AED 1,345
      • MYR 14:19
        5h 21m
        1 stop
        EYW 19:40
        Myrtle Beach - Key West | Fri, Jan 23 | Delta Air Lines
        EYW 18:06
        19h 24m
        1 stop
        MYR 13:30
        Key West - Myrtle Beach | Sun, Jan 25 | Delta Air Lines
        AED 1,410
        55% OFF
        AED 3,160 AED 1,410
      • MYR 06:00
        5h 43m
        1 stop
        EYW 11:43
        Myrtle Beach - Key West | Tue, Dec 16 | Delta Air Lines
        EYW 18:20
        15h 50m
        1 stop
        MYR 10:10
        Key West - Myrtle Beach | Sat, Dec 20 | Delta Air Lines
        AED 1,422
        55% OFF
        AED 3,160 AED 1,422
      • MYR 07:00
        5h 7m
        1 stop
        EYW 12:07
        Myrtle Beach - Key West | Mon, Dec 22 | Delta Air Lines
        EYW 07:25
        5h 6m
        1 stop
        MYR 12:31
        Key West - Myrtle Beach | Fri, Dec 26 | Delta Air Lines
        AED 1,447
        54% OFF
        AED 3,160 AED 1,447
      • MYR 13:18
        6h 25m
        1 stop
        EYW 19:43
        Myrtle Beach - Key West | Wed, Dec 24 | Delta Air Lines
        EYW 07:25
        5h 6m
        1 stop
        MYR 12:31
        Key West - Myrtle Beach | Wed, Dec 31 | Delta Air Lines
        AED 1,479
        53% OFF
        AED 3,160 AED 1,479
      • MYR 15:39
        5h 19m
        1 stop
        EYW 20:58
        Myrtle Beach - Key West | Sun, Dec 21 | Delta Air Lines
        EYW 07:25
        26h 59m
        1 stop
        MYR 10:24
        Key West - Myrtle Beach | Sat, Dec 27 | Delta Air Lines
        AED 1,801
        43% OFF
        AED 3,160 AED 1,801
      • MYR 10:32
        6h 43m
        1 stop
        EYW 17:15
        Myrtle Beach - Key West | Wed, Dec 10 | Delta Air Lines
        EYW 07:40
        6h 15m
        1 stop
        MYR 13:55
        Key West - Myrtle Beach | Sun, Dec 14 | Delta Air Lines
        AED 2,212
        30% OFF
        AED 3,160 AED 2,212
      • MYR 13:00
        17h 25m
        1 stop
        EYW Invalid Date
        Myrtle Beach - Key West | Thu, Dec 11 | Normal Airline
        EYW 15:00
        6h
        Direct
        MYR 16:00
        Key West - Myrtle Beach | Sat, Dec 13 | Normal Airline
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Displayed flight fares from Myrtle Beach to Key West are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Flight details for Myrtle Beach to Key West

The distance between Myrtle Beach and Key West is 1,053.01km. Based on Trip.com's data, travel demand peaks in October. The off-season for travel is November.

Cheapest direct flight priceAED 423
Cheapest return ticket priceAED 982
Off-season for travelNovember
Peak season for travelOctober
Flight distance1,053.01km

Find the best time to fly from Myrtle Beach to Key West

The cheapest time for Myrtle Beach to Key West flights: Dec 28 to Jan 4 — one way flight prices from AED 422.

Cheapest flights
From price
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  • 714
  • 1421
  • 2128

  • Jan

    284
  • 411
  • 1118
  • 1825

  • Feb

    251
  • 18
  • 815
  • 1522

  • Mar

    221
Displayed fare trends are based on Trip.com's aggregated average of the lowest flight prices from Myrtle Beach to Key West, calculated over the upcoming 10 weeks.

Flight FAQs

  • Which airlines offer the cheapest flights from Myrtle Beach (MYR) to Key West (EYW)?

    Based on Trip.com data, Delta Air Lines offers one-way fares as low as AED 423 on Cheapest nonstop routes (e.g. MYR to EYW on Thu, Jan 1), while Delta Air Lines offers Cheapest nonstop round-trips from AED 982 departing on Sat, Dec 13 and returning on Wed, Dec 17.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Myrtle Beach to Key West is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Myrtle Beach to Key West, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Jan 1, with one-way flights priced at just AED 423.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Delta Air Lines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Key West travel is around October.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Myrtle Beach to Key West is November, when demand for travel is lower.
  • After crunching the numbers on our December flight calendar, it's currently cheapest to fly from Myrtle Beach to Key West on December 13, 2025 with Delta Air Lines, with prices starting at AED 982.
  • The time difference between Key West and Myrtle Beach is 0h.
  • Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

More Flight Itineraries