聖地亞哥動物園附近有這幾間酒店：聖迭戈威斯汀酒店(The Westin San Diego),聖迭戈貝斯特韋斯特優質海邊酒店(Best Western Plus Bayside Inn San Diego),威斯汀聖迭戈瓦斯燈街區酒店(The Westin San Diego Gaslamp Quarter),蓋斯蘭姆普會議中心舒適酒店(Comfort Inn Gaslamp Convention Center),拉斐特泳池俱樂部及簡易別墅酒店(The Lafayette Hotel, Swim Club & Bungalows)